LATEST NEWS older news

With the Waters Corp., we describe a new device for separations at -20 °C, published for Jim Jorgensen's birthday by the Journal of Chromatography A.    

A collaboration with Kenneth Westover at UT Southwestern uncovers familial relationships in Ras-family proteins.  Read the full article here.

Northeastern University College of Science explains our recent partnership with Prof. Timothy Springer of Children's Hospital Boston. News story.

Sandia National Laboratories features our long-standing collaboration with Dr. Mike Kent studying the conformation of HIV Nef at the membrane.  Read the story here.


The laboratory of John R. Engen at Northeastern University performs research at the interface of Analytical Chemistry, Biochemistry & Structural Biology.


We use hydrogen exchange and mass spectrometry (HX MS) as our core technology to probe protein conformation, conformational changes, dynamics, protein folding and the effects of binding.

In the past 15 years, we have applied HX MS to the study of over 100 proteins.