ASMS 2008 POSTERS:

 
 
PRESENTATIONS AT
THE 56th ANNUAL CONFERENCE OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
JUNE 1 - JUNE 5, DENVER, COLORADO

Code: Tuesday - TOE pm
Time Slot/Poster Number: 2:50 pm
Session: H/D Exchange and Protein Folding - Four Season Ballroom 1-2 
Probing the Conformation and Dynamics of a Monoclonal Antibody by Hydrogen-Deuterium Exchange Mass Spectrometry
DAMIAN HOUDE1,2; Steven Berkowitz2; Marek Kloczewiak2; Rohin Mhatre2; Thomas Wales1; John R. Engen1;
1Northeastern University, Boston, MA; 2Biogen Idec, Inc., Cambridge, MA

Code: Wednesday - WPTTT
Time Slot/Poster Number: 480
Session: Protein Conformation HD Exchange I - Poster Hall
Hydrogen exchange shows that phosphorylation of c-Abl Tyr 89 disrupts downregulatory intramolecular interactions
SHUGUI CHEN1; Thomas E. Smithgall2; John R. Engen1
1Northeastern University, Boston, MA; 2University of Pittsburgh School of Medicine, Pittsburgh, PA

Code: Wednesday - WPTTT
Time Slot/Poster Number: 486
Session: Protein Conformation HD Exchange I - Poster Hall
The effects of mutation and inhibitor binding on Abl kinase conformation by hydrogen deuterium exchange mass spectrometry
ROXANA E. IACOB1; Teodora Pene-Dumitrescu2; Nathanael S. Gray3; Thomas E. Smithgall2; John R. Engen1;
1Northeastern University, Boston, MA; 2University of Pittsburgh School of Medicine, Pittsburgh, PA; 3Dana- Farber Cancer Institute, Harvard Medical School, Boston, MA

Code: Wednesday - WPTTT
Time Slot/Poster Number: 488
Session: Protein Conformation HD Exchange I - Poster Hall
Conformational Analysis of the HIV-1 viral infectivity factor (Vif) Protein using Hydrogen Exchange Mass Spectrometry
SEAN R. MARCSISIN1; Dana Gabuzda2; K.S. Rajendran2; Andrew J. Brazier2; John R. Engen1
1Northeastern University, Boston, MA; 2Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

Code: Thursday - ThPTTT
Time Slot/Poster Number: 493
Session: Protein Conformation H/D Exchange II - Poster Hall 
Recent advances in UPLC for hydrogen exchange mass spectrometry: high-speed & high-resolution separations at zero degrees celsius
THOMAS E. WALES1; Keith Fadgen2; Geoff Gerhardt2; John R. Engen1
1Northeastern University, Boston, MA; 2Waters Corporation, Milford, MA

Code: Thursday - ThPU
Time Slot/Poster Number: 510
Session: Proteins - General, Methods - Poster Hall 
The Specificity of Pepsin for Proteolytic Digestion and MS Applications
MELISSA H. PALASHOFF1; Martha Stapels2; Keith Fadgen2; John R. Engen1
1Northeastern University, Boston, MA; 2Waters Corporation, Milford, MA