ASMS 2009 POSTERS:

PRESENTATIONS AT
THE 57th ANNUAL CONFERENCE OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
May 31 - June 4, Philadelphia, PA

Code: - TPN
Time Slot/Poster Number: 332
Session: LC/MS Sample Preparation
Assessing the variability of peptide peak areas in online pepsin digestion
Joomi Ahn1; Martha Stapels1; Keith Fadgen1; John R. Engen2
1Waters Corporation, Milford , MA; 2Northeastern University, Boston, MA

Code: - TPS
Time Slot/Poster Number: 430
Session: Protein Conformation I
Towards a standardized approach in presenting hydrogen-deuterium exchange mass spectrometry (HDX MS) data in comparability studies of biopharmaceutical products
Cedric Bobst1; Rinat Abzalimov1; Damian Houde2,3; Marek Kloczewiak2; Steven A. Berkowitz2;
John R. Engen3; Igor A. Kaltashov1
1University of Massachusetts, Amherst , MA; 2Biogen Idec, Inc., Cambridge, MA; 3Northeastern University, Boston, MA

Code: - TPS
Time Slot/Poster Number: 436
Session: Protein Conformation I
Structural and dynamic investigation of umuD gene products by hydrogen exchange mass spectrometry
Jing Fang; Penny J. Beuning; John R. Engen
Northeastern University, Boston, MA

Code: - TPS
Time Slot/Poster Number: 438
Session: Protein Conformation I
The interaction of myristoylated HIV Nef with N-myristoyltransferase-1 as determined by hydrogen exchange mass spectrometry
Chris Morgan1; Purushottam S. Narute2; Brian V. Miglionico1; Thomas E. Smithgall2;
John R. Engen1
1Northeastern University, Boston , MA; 2University of Pittsburgh, Pittsburgh, PA

Code: - TPS
Time Slot/Poster Number: 440
Session: Protein Conformation I
On the conformational dynamics of the HIV-1 Vif:Elongin BC ternary complex
Sean R. Marcsisin; John R. Engen
Northeastern University, Boston, MA

Code: - TPS
Time Slot/Poster Number: 441
Session: Protein Conformation I
Post-translational modifications alter intact IgG1 conformation and influence Fc-gamma-RIII binding
Damian Houde1,2; Steven Berkowitz1; John R. Engen2
1Biogen Idec, Inc., Cambridge , MA; 2Northeastern University, Boston, MA

Code: - TPS
Time Slot/Poster Number: 449
Session: Protein Conformation I
Allosteric effects in the Abl kinase upon inhibitor binding
Roxana E. Iacob1,3; Jianming Zhang2; Nathanael S. Gray2; John R. Engen1,3
1Northeastern University, Boston, MA; 2Dana-Farber Cancer Institute, Harvard Medical, Boston, MA; 3Barnett Institute, Boston, MA  

Code: - TOG pm
Time Slot/Poster Number: 2:50 pm
Session: HDX for Protein Structure and Folding
On the conformation of HIV-1 Nef from various viral strains
Thomas E. Wales1; Lori Emert-Sedlak2; Thomas E. Smithgall2; John R. Engen1
1Northeastern University, Boston , MA; 2University of Pittsburgh School of Medicine, Pittsburgh, PA

Code: - WPR
Time Slot/Poster Number: 421
Session: Protein Conformation II
Rapid gas-phase deuterium labeling in a traveling wave ion guide for enhanced detection of protein conformations
Kasper D. Rand1; Steven D. Pringle2, Jeff Brown2, James P. Murphy III2; Keith Fadgen2;
John R. Engen1
1Northeastern University, Boston , MA; 2Waters Corporation, Milford, MA & Wythenshawe, Manchester, UK